陈皮挥发油·β-环糊精包合物在冲剂生产中的应用

Application of Citrus Reticulata Volatile Oil-beta-cyclodextrin Inclusion Complex in Manufacture Practice of Granules

运用正交试验，以挥发油利用率为主要指标筛选出制备陈皮挥发油·β-环糊精包合物中试研究的最佳包合条件：β-环糊精和油的比例为6：1，包合温度为50℃，包合时间2h。将其用于复方陈皮冲剂的制备工艺改进，并以挥发油含量为指标对产品的稳定性进行了初步考察。

Inclusion complex was used in the preparation of granules to prevent the volatilization of oil. The optimum conditions for the preparation were investigated by orthogonal test. The rate of oil utilization was used as a major criterion to evaluate the inclusion effeets. Results showed that by stirring a mixture of 6: 1 β-cyclodextrin and oil at 50 ℃ for two hours gave the best result. The production process was tried in the preparation of compound citrus reticulata oil granules and showed satis factory results. The stability of the granules was preliminary observed.