2008年昌平区公共卫生从业人员HBsAg携带分析

Analysis of HBsAg in public health staff in Changping in 2008

目的：了解昌平区公共卫生从业人员乙肝病毒的感染情况,更好地指导公共卫生从业人员的疾病预防工作。方法：采用酶联免疫吸附试验（ELISA法）对昌平辖区内公共卫生从业人员乙肝感染标记物进行检测。结果：昌平区2008年1月1日-12月31日公共卫生从业人员HBsAg阳性率1.99%,男性HBsAg携带率比女性高（χ^2=869.98,P〈0.01）。HBsAg阳性合并HBeAg、抗-HBc阳性是感染的主要模式,占22.20%。公共卫生从业人员来源本地与外埠的HBsAg阳性率分别为0.85%、2.36%,经统计学分析,两率差别有统计学意义（χ^2=188.66,P〈0.01）。结论：昌平区公共卫生从业人员乙型肝炎病毒感染率低于普通人群感染率（4.4%-8.0%）,外埠HBsAg阳性率比本地高。说明我区几年来的公共卫生监管力度到位,继续开展公共卫生从业人员每年的健康体检和在从业人员中加强乙肝疫苗的预防接种有着重要意义。

Objective：To investigate the HBV infection in public health staff in Changping in 2008 to provide basis for guidance of prevention. Methods： ELISA was used to detect HBV DNA in blood samples from the staff. Results： The positive rate of HBsAg was 1.99% during the year of 2008 but it was significantly higher in the males than in females （ P 〈 0. 01 ）. The major infection mode was positive HBsAg in combination with positive HBeAg and anti - HBc positivity （22.20%）. The positive rate of HBsAg was markedly higher in those staff coming from other districts than in those native inhibiting staff （P 〈 0. 01 ）. Conlcusion：Continual monitoring of HBV infection is very important for public health staff .