羊红膻根的化学成分研究

Studies on the Chemical Constituents of the Root of Pimpinella thettungiana

从羊红膻(Pimpinella thellungiana Wolff.)根中分得四个化合物,经理化常数测定和光谱数据解析证明为棕榈酸(Ⅰ)、4-丙烯基苯酚(Ⅱ)、松酯酚(Ⅲ)和新化合物2-甲基-2-羟基-5-甲氧基苯并[d]氢化呋喃-3-酮(Ⅳ)。

Four compounds were isolated from the roots of Pimpinella thelliaigiana Wolff. , their structures were identified as palmitic acid(Ⅰ) , 4-propenylphenol(Ⅱ), pinoresinol(Ⅲ), 2-methyl-2-hydroxy-5-methoxy berzo(d) hydrofuran-3-one(Ⅳ) by physicochemical constants and spectral analysis (UV, IR, MS/1HNMR/13CNMR,13C-1HCOSY, DEFT), Ⅳ of them is a new compound, Pharmacological tests showed Ⅳ has a hypotensive effect.