摘要
目的对Ⅰ期子宫内膜癌术后放疗的意义和放射并发症等进行探讨。方法1986年5月~1995年12月收治Ⅰ期子宫内膜癌20例,均经术后病理证实。15例行子宫全切及双附件切除术,5例加盆腔淋巴结清扫。20例均行术后放疗,大部分患者术后2~4周开始放疗,照射野包括全部盆腔淋巴结。全盆腔DT40~50Gy。全部患者得到随访。结果3,5,10年生存率分别为10/10、8/9、3/4,局控率100%(20/20)。5年远转率5%(1/20)。20例在放疗过程中均出现不同程度的急性放射并发症,6例有晚期放射并发症,其中2例较严重。结论术后放疗对提高局控率有利,但晚期损伤发病率相对较高。
Objective To evaluate the role and complications of adjuvant radiotherapy for stage I endometrial cancer after surgery. Methods From May, 1986 to December, 1995, 20 patients with stage I endometrial cancer received total abdominal hysterectomy with bilateral salpingo oophorectomy(TAH/BSO), and additional pelvic lymph node dissection in 5 cases. Most of the patients received radio therapy in 2~4 weeks after surgery. The radiation fields included pelvic lymph nodes with a total dose of 40~50 Gy. Results All the patients had survived for 10 years. Only one patient developed distant metastases. Acute radiation reaction was observed in all patients. Late radiation induced damage occured in six patients and was severe in two. Conclusion Postoperative radiotherapy in the management of stage I endometrial cancer is beneficial for the controal of local recur rence but has relatively high frequency of late radiation injury.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
1998年第3期233-234,共2页
Chinese Journal of Oncology
关键词
子宫肿瘤
子宫内膜癌
手术后
放射疗法
Endometrial neoplasms/radiotherapy Endometrial neoplasms/radiotherapy Radiation injuries