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胎儿染色体异常诊断方法的研究进展 被引量：12

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摘要 胎儿细胞培养、染色体核型分析是胎儿染色体异常最经典的检测方法。诊断的准确性在培养的羊水细胞中可达99．4％～99．8％，绒毛取样（chorionic villus sampling，CVS）培养为97．5％～99．6％。但对小于10Mb碱基的染色体片段缺失或重复，普通核型难以检出，即使是高分辨染色体核型有时也难作出确切诊断。由于G显带本身的特点，
作者 朱湘玉 胡娅莉
机构地区 南京大学医学院附属南京市鼓楼医院妇产科
出处 《中华围产医学杂志》 CAS 2009年第2期105-108,共4页 Chinese Journal of Perinatal Medicine
关键词 胎儿染色体异常 诊断方法 染色体核型分析 细胞培养 染色体片段 羊水细胞 绒毛取样 高分辨
分类号 R714 [医药卫生—妇产科学]
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参考文献39

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二级参考文献19

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共引文献17

同被引文献69

  • 1顾芳,秦宜德,罗欣.细胞凋亡检测方法的研究进展[J].医学信息（医学与计算机应用）,2014,0(10):517-518. 被引量：3
  • 2韩美艳,俞冬熠,姜楠,任慧颖.影响羊水细胞培养成功率因素的分析[J].中国产前诊断杂志（电子版）,2014,6(3):42-45. 被引量：8
  • 3化爱玲,张月莲,郑梅玲,张桂林.孕中期羊水细胞染色体核型分析在产前诊断中的应用[J].中国优生与遗传杂志,2007,15(1):34-35. 被引量：8
  • 4李琳.染色体臂间倒位的遗传效应分析[J].中华医学遗传学杂志,2007,24(4):487-488. 被引量：17
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引证文献12

二级引证文献32

中华围产医学杂志
2009年 第2期

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