妊娠期糖尿病筛查3280例结果分析

Analysis of 3280 cases of gestational diabetes mellitus challenge test.

目的初步了解本地妊娠期糖尿病(GDM)和妊娠期糖耐量受损(GIGT)的患病率;探讨糖筛查试验和空腹血糖两种方法对妊娠期糖尿病筛查的意义。方法对3280例孕24～28周孕妇进行口服50g葡萄糖负荷试验(GCT),对1h静脉血糖≥7.8mmol/L者做75g口服葡萄糖糖耐量试验(OGTT)。结果本地GDM患病率为2.16%;GIGT的患病率为4.82%;GCT异常率为28.23%;空腹血糖作为筛查方法的漏诊率为22.53%,敏感性差。结论本地GDM和GIGT有一定的患病率,应重视和加强筛查工作。糖筛查试验应作为妊娠期产前检查的常规项目,对临床早期诊断妊娠期糖尿病具有重要意义。

Objective： To investigate the local sicken rate of Gestational diabetes mellitus （ GDM）, and to discuss the meaning of Glucose Challenge Test （GCT） and fast blood glucose （FBG） for GDM. Methods： Do 50g Oral Glucose Challenge Test on 3280 pregnant women who have been pregnant for 24 -28 weeks, then do 75g Oral Glucose Tolerance Test on woman whose lh Venous blood glucose is larger than 7.8mmol/L. Results： The abnormal rate of GCT is 28. 23%, and diagnose 71 women who gain Gestational diabetes mellitus. The rate of GDM is 2. 16%. Conclusions： GDM possibly happens in local, so we should reinforce the work of challenge test. Glucose Challenge Test is supposed to be a conventional project of prenatal examinations. Glucose Challenge Test has a practical significance for early diagnosis of gestational diabetes mellitus.