摘要
三硝基甲苯（ＴＮＴ）染毒小鼠肝组织光镜检查见肝细胞水肿，嗜酸性变及肝瘀血，部分肝细胞呈点状坏死；小鼠ＴＮＴ染毒的同时，口服给予没食子酸丙酯（ＰＧ），发现肝组织病变程度显著减轻，肝细胞再生明显，表明ＰＧ对ＴＮＴ中毒性肝损伤具有一定防治作用。
n addition to the hepatocellular edema and cytoplasmic eosinophilia,sludging of blood was present in liver of mice exposed to trinitrotoluene(TNT).Single necrosis of the partical liver cell was seen occasionally.Liver damage induced by TNT was significantly alleviated by orally administrated propyl gallate(PG).Futhermore,PG can promote the regeneration of the hepatocytes following TNT exposed mice.The results suggest that PG showed a protective effect on the histopathologic changes of liver injury induced by TNT.
出处
《卫生研究》
CAS
CSCD
北大核心
1998年第3期151-153,共3页
Journal of Hygiene Research
基金
兵器工业总公司卫生处资助
