头孢吡肟在玻碳电极上的电化学行为研究

Study on electrochemical behaviour of cefepime at glassy carbon electrode

在0．1mol·L^-1KH2PO4-NaOH（pH=8．0）介质中，头孢吡肟在玻碳电极上产生-灵敏的氧化峰，其峰电流Ip与头孢吡肟在5．2×10^-6-2．6×10^-5mol·L^-1内有良好的线性关系（r=0．9996），检出限为5．13×10^-9mol·L^-1，回收率98．33％，RSD为2．12％．用线性扫描和循环伏安法研究了体系性质，结果表明，头孢吡肟的电极过程为具有吸附的不可逆过程，电极反应转移电子数为2．

In a medium of 0. 1 mol · L^-1 KH2PO4 of cefepime（CFPM） was obtained by glassy carbon - NaOH （ pH = 8.0）, the sensitive oxidation peak electrode. A sensitive oxidation peak of CFPM was found at glassy carbon electrode. The linear range between the peak current and the concentration of CFPM was between 5.2×10^-6-2.6×10^-5mol·L^-1 （r = 0. 999 6） with the detection limit as 5.13 ×10^-9 mol ·L^-1 , the recovery of CFPM was 98.33%, RSD was 2.12%. The electrochemical behavior of the system was studied at glassy carbon electrode by linear sweep and CFPM. The electrode reduction process of CFPM at glassy carbon electrode was irreversible with adsorptive characteristics. Two electrons are transferred in all electrode reaction.