潘托拉唑应用脑卒中吸入性肺炎130例临床分析

Effect of pantoprazole on the incidence of aspiration pneumonia in 130 stroke patients

目的:探讨潘托拉唑对脑卒中患者吸入性肺炎发生率的影响。方法:回顾130例脑卒中患者,根据其是否使用潘托拉唑将其分为常规治疗组和潘托拉唑组,分别统计2组患者吸入性肺炎的发生率。结果:潘托拉唑组脑卒中患者吸入性肺炎发生率为59.34%,明显高于常规治疗组30.78%(P<0.05)。结论:潘托拉唑能增加脑卒中患者吸入性肺炎的发生率;临床中须严格把握其在脑卒中患者的适应证。

OBJECTIVF To investigate the effect of pantoprazole on the incidence of aspiration pneumonia in stroke patients. METHODS The 130 stroke patients were divided into two groups： conventional group and pantoprazole group. And calculated the incidence of aspiration pneumonia respectively. RESULTS The incidence of aspiration pneumonia in pantoprazole group was 59. 34% which is significantly higher than conventional group 30. 78% （P〈0. 05）. CONCLUSION Intravenous pantoprazole can increase the incidence of aspiration pneumonia in stroke patients. Pantoprazole needs to be indicated strictly in stroke patients.