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NKT细胞的发育分化及细胞因子分泌状态的调控机制 被引量：6

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作者 周志侠 张彩
机构地区 山东省医学科学院基础医学研究所 山东大学药学院免疫药理与免疫治疗研究所
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2009年第6期568-570,共3页 Chinese Journal of Cellular and Molecular Immunology
基金 国家重点基础研究发展计划(973)资助项目(2007CB815800) 国家自然科学基金重大研究计划资助项目(90713033)
关键词 NKT细胞 CD1D IFN-Γ IL-4 APC
分类号 Q546 [生物学—生物化学] R915 [医药卫生—微生物与生化药学]
  • 相关文献

参考文献19

  • 1Matsuda JL,Mallevaey,Scott-Browne J,et al.CD1d-restricted iNKT cells,the 'Swiss-Army knife' of the immune system[J].Curr Opin Immunol,2008,20(5):1-11.
  • 2Godfrey DI,Berzins SP.Control points in NKT-cell development[J].Nat Rev Immunol,2007,7(7):505-518.
  • 3刘景华,于力.NKT细胞研究进展[J].细胞与分子免疫学杂志,2008,24(2):194-196. 被引量：18
  • 4Matsuda JL,Gapin L.Developmental program of mouse Val4i NKT cells[J].Cur Opin Immunol,2005,17(2):122-130.
  • 5Benlagha K,Wei DG,Veiga J,et al.Characterization of the early stages of thymic NKT cell development[J].J Exp Med,2005,202(4):485-492.
  • 6Griewank K,Borowski C,Rietdijk S,et al.Homotypic interactions mediated by Ly108 and SLAM control NKT lineage development[J].Immunity,2007,27(5):751-762.
  • 7Matsuda JL,Zhang Q,Ndonye R,et al.T-bet concomitantly controls migration,survival,and effector functions during the development of Vα14i NKT cells[J].Blood,2006,107(7):2798-2805.
  • 8Townsend MJ,Weinmann AS,Matsuda JL,et al.T-bet regulates the terminal maturation and homeostasis of NK and Vα14i NKT cells[J].J Exp Med,2006,203(3):755-766.
  • 9Kim PJ,Pai SY,Brigl M,et al.GATA-3 regulates the development and function of invariant NKT cells[J].J Immunol,2006,177(10):6650-6659.
  • 10Eger KA,Sundrud MS,Motsinger AA,et al.Human natural killer T cells are heterogeneous in their capacity to reprogram their effectors functions[J].PLoS ONE,2006,1(1):1-9.

二级参考文献20

  • 1Godfrey DI, Macdonald HR, Kronenberg M, et al. NKT cells: what's in a name? [ J ]. Nat Rev Immunol, 2004, 4 (3) : 231 - 237.
  • 2Kronenberg M, Engel I. On the road: progress in finding the unique pathway of invariant NKT cell differentiation[ J]. Curr Opin Immunol, 2007, 19(2) : 186 - 193.
  • 3Kronenberg M, Gapin L. The unconventional lifestyle of NKT cells [J]. Nat Rev Immunol, 2002, 2(8) : 557 -568.
  • 4Baev DV, Peng XH, Song L, et al. Distinct homeostatic requirements of CD4^+ and CD4^- subsets of Vα24-invariant natural killer T cells in humans[J]. Blood, 2004, 104(13) : 4150 -4156.
  • 5Ragin M J, Sahu N, August A. Differential regulation of cytokine production by CDld-restricted NKT cells in response to superantigen staphylococcal enterotoxin B exposure [ J ]. Infect Immun, 2006, 74 ( 1 ) : 282 - 288.
  • 6Zhou D, Mattner J, Cantu C, et al. Lysosomal glycosphingolipid recognition by NKT cells[J]. Science, 2004, 306(5702) : 1786 - 1799.
  • 7Porubsky S, Speak AO, Luckow B, et al. Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide ( iGb3 ) deficiency [ J ]. Proc Natl Acad Sci USA, 2007, 104(14) : 5977 -5982.
  • 8Wang ZY, Kusam S, Munugalavadla V, et al. Regulation of Th2 cytokine expression in NKT cells : unconventional use of Stat6, GATA-3, and NFAT21[J]. J Immunol, 2006, 176(2): 880 -888.
  • 9Lee PT, Benlagha K, Teyton L, et al. Distinct functional lineages of human Vα24 natural killer T cells[J]. J Exp Med, 2002, 195(5) : 637 - 641.
  • 10Thomas SY, Hou R, Boyson JE, et al. CDld-restricted NKT cells express a chemokine receptor profile indicative of Th1 -type inflammatory homing cells[J]. J Immunol, 2003, 171 (5) : 2571 -2580.

共引文献17

同被引文献39

  • 1张军红,徐酉华.特发性血小板减少性紫癜发病机制研究进展[J].实用儿科临床杂志,2009,24(9):700-702. 被引量：15
  • 2刘原兴,吕毅.Th2类细胞因子在移植免疫中作用的研究[J].医学综述,2004,10(8):453-455. 被引量：1
  • 3赵晓彬,晏晓明,杨松霖.Th1/Th2细胞因子mRNA的表达与角膜缘移植排斥的关系[J].眼科研究,2007,25(6):419-423. 被引量：5
  • 4Berzofsky JA, Terabe M. NKT cells in tumor immunity : opposing subsets define a new immunoregulatory axis [ J]. J Immunol, 2008, 180 (6) : 3627 -3635.
  • 5D'Andrea A, Goux D, De Lalla C, et al. Neonatal invariant Vα24 + NKT lymphocytes are activated memory cells [ J ]. Eur J Immunol, 2000, 30(6) : 1544 -1550.
  • 6Taniguchi M, Seino K, Nakayama T. The NKT cell system: bridging innate and acquired immunity [ J ]. Nat Immunol, 2003, 4 ( 12 ) : 1164 - 1165.
  • 7Onoe K, Yanagawa Y, Minami K, et al. Thl or Th2 balance regulated by interaction dendrite cells and NKT cells [ J ]. Immunol Res, 2007, 38(1 -3) : 319 -332.
  • 8Niemeyer M, Darmoise A, Mollenkopf H J, et al. Natural killer T-cell characterization through gene expression profiling : an account of versatility bridging T helper type 1 ( Thl ) , Th2 and Th17 immune responses[J]. Immunology, 2007, 123(1 ) : 2171 -2180.
  • 9Baloto A, Unutmaz D, Gaspari AA, et al. Natural killer T ceils : An unconventional T-cell subset with diverse effector and regulatory functions[J]. J Invest Dermatol, 2009, 73( 1 ) : 39 -45.
  • 10Peralbo E, Alonso C, Solana R. Invariant NKT and NKT-like lymphocytes: two different T cell subsets that are differentially affected by ageing[J]. Exp Gerontol, 2007, 42(8) : 703 -708.

引证文献6

二级引证文献18

细胞与分子免疫学杂志
2009年 第6期

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