老年人多发性骨髓瘤41例实验室特点分析

Analysis to Laboratory Chracteristis of Elderly 41 Cases with the Multiple Myeloma

目的系统观察老年人多发性骨髓瘤（MM）实验室指标特点，为老年人MM的诊断和治疗提供依据。方法分析41例老年人MM患者多项实验检查结果，包括血液和骨髓形态学等。结果骨髓瘤细胞在骨髓中占的比值与其对骨髓的损伤程度成正比。36例（87．8％）蛋白电泳呈现M蛋白，32例（78．0％）血清球蛋白增高；血沉异常36例（87．8％），血红蛋白降低31例（75．6％），尿本周氏蛋白阳性20例（48．8％）；IgG型25例，IgA型14例。结论血液和骨髓形态学检查的综合分析，有助于老年MM患者的早期快速诊断、分型及鉴别诊断。

Objective To discuss the some laboratory indexes characteristics of elderly patients with multiple myeloma. Method Accoding to many experimental diagnoses of elderly patientswith the multiple myeloma. Result The group were found in bone marrow as myeloma cells. There are 36 cases （87.8%）with proteins Electrophoresis presenting M proteins, 32 cases（78. 1%） with serum globins elevation,36 cases （87.8%）with higher sedimentation rate of the red blood cell, 31eases （75.6 % ） with hematoglobin fall, 20 cases （48.8%）with Bence-jones proteins in urine, 25 cases with immunology type IgG,14 cases with immunology type IgA. Conclusion Cyto-morphology and many experimental diagnoses have significant implications for early MM,rapid typing and differentiating diagnosis.