摘要
Lemierre综合征是源自感染性栓塞性颈内静脉炎的急性、全身性、化脓性疾病，坏死梭菌是最主要致病菌，最常继发于口咽感染。由于可累及全身各脏器，临床表现无特异性，极易误诊、漏诊。根据感染性栓塞性颈内静脉炎的症状、体征或影像学检查结果，结合血行感染或远处化脓病灶证据，可明确诊断。推荐早期、足量、足疗程并且覆盖厌氧菌的联合抗感染治疗。
Lemierre syndrome is an acute systemic suppurative infection originating from internal jugular vein septic thrombophlebitis most commonly as sequel to oropharyngeal infection, with Fusobacterium necrophorum as its most common pathogen. It is prone to misdiagnosis or under-diagnosis due to its lack of specific clinical manifestations, arising from multi-organ involvement. Diagnosis can be established based on positive findings of internal jugular vein septic thrombophlebitis from history collection, physical examination or imaging studies, in combination with evidence of hematogenous infection or metastatic abscesses. Early, sufficient and prolonged course of antimierobial therapy covering anaerobic bacteria is recommended.
出处
《国际呼吸杂志》
2009年第11期688-691,共4页
International Journal of Respiration
