271例新疆南部维吾尔族患者尿结石成分分析与代谢评价

Analysis on chemical composition of urinary stones and evaluation on metabolic disturbance in 271 Uygur patients of south Xinjiang

目的:探讨新疆南部维吾尔族泌尿系结石患者结石成分与代谢异常的关系。方法:分析271例泌尿系结石患者的结石成分及其中177例24h尿分析,并将二者结合作初步评价。结果:草酸钙结石214例(78.9%),感染性结石7例(2.6%),尿酸结石29例(10.7%),磷酸盐结石17例(6.3%),胱氨酸结石4例(1.5%)。177例24h尿分析结果患者中代谢异常129例(72.9%),其中高钙尿症40例(22.6%),高尿酸尿症62例(35.0%),高草酸尿症43例(24.3%),高尿磷71例(40.1%),低枸橼酸尿症117例(66.1%),低尿镁症59例(33.3%),24h尿量<2000ml者72例(40.7%),高胱氨酸尿症2例(1.1%)。结论:结石成分及患者的代谢评价对泌尿系结石的成因、治疗和预防有重要的临床意义。

Objective： To study the relationship between chemical composition of urinary stones and metabolic disturbance in Uygur nationality of south Xinjiang. Methods： 271 urinary stone patients who had undergone analysis of stone composition were evaluated and 177 of them had 24-h urine analysis results. The relationship between stone composition and metabolic disturbance was analyzed by using X2 test. Results： Calcium oxalate stones were found in 214 cases（78.9 %）, infection stones in 7 cases （2.6 %）, uric stones in 29 cases （10.7 %）, phosphate stones in 17 cases （6.3 %） and cystine stones in 4 cases （1.5 %）. Metabolic disturbance was found in 129（72.9 %） of 177 patients with 24-h urine analysis results. Among the 129 patients, hyperealciuria occurred in 40 cases（22.6 %）, hyperuricosuria in 62 cases（35.0 %）, hyperoxaluria in 43 cases（24.3 %）, hyperphophauria in 71 cases （40.1%）, hypocitraturia in 117 cases （66.1%）, hypomagnesiuria in 59 cases （33.3 %）, 24 h urine volume〈2000ml in 72 cases （40.7 %）, hypercystinuria in 2 cases （1.1% ）. Conclusions： Stone composition and metabolic evaluation were very important in finding the causes and in treating and preventing urinary stones.