基于微线圈阵列的多道神经电刺激信号透皮传输的初步实验研究

Pilot study on microcoil-array-based multichannel transcutaneous transmission of neural electrical stimulation

通过探索微线圈阵列实现多路神经电刺激信号透皮传输的可行性及影响传输效率的相关因素。根据电磁耦合原理,设计了包括脉冲发生、高频振荡、AM调制、功率放大、选频等刺激信号发射电路,信号接收电路,以及用于多通道信号耦合的微线圈阵列和相应实验测试装置。实验中对电路的性能以及线圈发生横向失配和角形失配时电路的可靠性进行了测试,在此基础上设计了2×2阵列的多通道传输装置。结果表明在调谐网络的作用下通道间信号的干扰较小,各通道输出信号能满足神经电刺激的要求。该方法经试验验证具有可行性,可用作各类植入式医疗仪器刺激或者控制信号的多通道传输装置,具有广泛的应用前景。

This topic is to explore the feasibility of using microcoil array to achieve multichannel transcutaneous transmission of neural electrical stimulation and the relevant factors that impact the transmission efficiency. According electromagnetic coupling principle, we designed a circuit of electrical stimulation transmission, including pulse generator, high-frequency oscillation, amplitude modulation, power amplifier and tuning network, an electrical stimulation receiver, a microcoil-array used for muhichannel signal coupling and an experimental device for test. We first proved the performance and reliability of the circuit when there are horizontal or angular mismatches between transmitter and receiver coil. On this basis we designed a 2 × 2 array muhichannel transmission device and each channel chooses the carrier wave in different frequency. With the function of tune network, the output signal can meet the requirements of the electrical nerve stimulation and there is weak interference among the channels. This design is proved feasible and can be used in various implantable electrical devices for muhichannel stimulation or control signal transmission, and has broad application prospects.