CAPD合并腹膜炎的影响因素分析

Title Analysis of factors on CAPD related peritonitis

目的探讨持续性不卧床腹膜透析(CAPD)患者并发腹膜炎的影响因素。方法通过对118例行CAPD治疗的终末期肾脏病(ESRD)患者的随访和病例资料的分析,分别按原发病类型、文化程度、SGA评分、透析龄分组,观察不同组别中腹膜炎的发生率。结果①与文化程度高中以上组比较,高中以下组的腹膜炎发生率明显升高(1次/111病人月∶1次/50病人月),差异有统计学意义(P<0.05);②与营养良好组比较,营养不良组的腹膜炎发生率明显升高(1次/143病人月∶1次/48病人月),差异有统计学意义(P<0.001);③与透析龄12个月以上组比较,透析龄12个月以下的患者腹膜炎发生率明显升高(1次/77病人月∶1次/56病人月),差异有统计学意义(P<0.05);④与非糖尿病组比较,糖尿病组患者腹膜炎的发生率有升高的趋势(1次/83病人月∶1次/63病人月),但两组间差异无统计学意义(P>0.05)。结论文化程度、SGA评分和透析龄是CAPD患者并发腹膜炎的影响因素。

Objective To investigate the relevant factors of peritonitis in patients receiving continuous ambulatory peritoneal dialysis （CAPD）. Methods We retrospectively analyzed Nutritional status and laboratory data of peritonitis complicated with CAPD in 118 cases,who were admitted to Division of Nephrology, Affiliated Hospital of Ningxia Medical University from 2003 to 2008, groups were divided by primary disease type, education level, SGA score and dialytic time. Analysed the incidence of peritonitis in each group. Results （1）peritonitis incidence of patients of low educational attainment was significantly higher than that of Highly educated, the difference has statistical significance （P 〈 0.05） ;（2）the peritonitis incidence of malnutrition group was significantly higher than well - nourished （P 〈 0.001 ） ;（3）Compared with patients that dialytic time more than or equal to 12 month , patients dialysised less than 12 month have a higher incidence of peritonitis, the difference has statistical significance （P 〈 0.05 ） ;（4）in the group of primary disease type, the incidence of peritonitis was no significant difference （P 〉 0.05 ）. Conclusion Education, SGA score and dialytic time are considered as the factors of CAPD related peritonitis.