两种白茶的抗突变和体外抗癌效果

Comparative Study on Antimutagenic and in vitro Anticancer Activities between Two Kinds of White Tea and Green Tea

本实验对两种绿茶和两种白茶进行抗突变和体外抗癌效果评价。采用Ames实验对绿茶和白茶的抗突变特性进行比较,得出白茶的抗突变效果好于绿茶的结果。通过MTT实验验证其抗癌效果。在400μg/ml浓度处理下,白牡丹和白毫银针表现出对AGS和HT-29癌细胞的生长抑制效果好于龙井绿茶和云雾绿茶。由此得出,白茶的抗突变和体外抗癌效果好于绿茶。

Antimutagenic and antitumor effects of two kinds of green tea and white tea products were investigated by Ames test and MTT assay, respectively. Ethanolic extract of white tea displayed significantly higher antimutagenicity against N- methyl-N＇-nitro-N-nitrosoguanidine （MNNG）-induced mutation of nutrient deficiency strain TA 100 of Salmonella typhimurium than that of green tea at 1.25 mg/disc and 2.5 mg/disc. At the concentration of 400μg/ml, Baimudan white tea and Baihaoyinzhen white tea showed better inhibitory effects against the growth of AGS and HT-29 cancer cells than Longjing green tea and Yunwu green tea. These results suggest that the antimutagenic and anticancer effects of white tea are higher than those of green tea.