手术后残留的胶质瘤预后分析

Progostic analysis of postoperatively residual gliomas

目的:探讨手术未全切除的胶质瘤患者与全切除的转归差异。方法:回顾性分析2000年1月-2004年1月108例未能手术全切除的胶质瘤患者,对预后进行单因素及多因素分析并与同期全切除的223例病例进行比较。结果:低级别组中手术未全切除的胶质瘤患者1,3年生存率与全切组无明显差异,5年生存率出现明显差异,全切组明显高于未全切组。高级别组中研究组与对照组的1年生存率差别不明显,3年及5年生存出现明显差异。结论:无论高低级别手术全切与否与胶质瘤复发及患者预后的关系极为密切。

Objective： To compare the clinical results of brain malignant glioma treated with total rernaoval and partial remaoval. Method： Integrated clinical data were analyzed retrospectively rrom 2000 Jan. to 2004 Jan., including the 108 patients of brain gliomas with partial removal （study group： lowgrade and high - grade gliomas） and 203 cases with total removal （control group）. 1 -, 3 - .and 5 - years survival rates of two groups were compared. Results： Of the patients with low - grade gliomas, 1 -, 3 - years survival rates of study group had no signiicant difference with control group （P〈 0.05） . and 5 - year survival rates of control group were significantly higher thean those of study group （P〈0. 01）. Of the ptients with high - grade gliornas, 1 - years survival rates of study group had no significant difference with control group （P〉0. 05）, and 3 -, 5 - year survival rates of control group were significanttly higher than those of study group （P〈0. 01）. Conclusion： Total remaoval should be emphasized.