小儿利咽康颗粒剂抗炎作用的实验观察

Experimental observation on anti-inflammation of Liyankang granule for children

目的观察小儿利咽康颗粒剂的抗炎作用。方法采用皮下注射5-羟色胺所致大鼠毛细血管通透性增加法、皮下注入角叉莱胶致大鼠足跖肿胀法、皮下埋藏无菌滤纸片致大鼠肉芽肿增生法,观察小儿利咽康颗粒剂的抗炎作用。结果利咽康颗粒各剂量组对5-羟色胺所致毛细血管通透性、对角叉莱胶致大鼠足跖肿胀、对大鼠肉芽肿增生均有抑制作用。结论小儿利咽康颗粒剂具有抗炎作用。

Objective To observe the anti-inflammatory effect of Liyankang granule for children. Methods Observe the anti-inflammatory effect by using subcutaneous injection of 5-HT to cause the rats＇ blood capillary permeability to heighten, of Carrageenin（Car） to cause proliferation of the rats＂ metatarsal bones,and by using the rats＂ subcutaneous implantation of sterile filter residue to cause the rats＂ granuloma. Results Liyankang granule for children could obviously inhibit blood capillary permeability caused by 5-HT and had effect on acute and chronic inflammation. Conclusion Liyankang granule for children has the antiinflammatory effect.