四妙汤加味合别嘌呤醇治疗高尿酸血症40例临床观察

Clinical Observation of Simiao Jiawei Decoction and Allopurinol Treated in patients with Hyperuricemia

目的:探讨四妙汤加味方对湿热型高尿酸血症尿酸的影响。方法:80例患者随机分为两组,治疗组和对照组各40例,治疗组采用四妙汤加味合别嘌呤醇治疗,对照组采用别嘌呤醇治疗,疗程为2周,观察两组治疗前后尿酸水平的变化。结果:两组治疗后血尿酸降低和尿尿酸升高与治疗前比较差异有显著性意义(P<0.05),治疗组血尿酸降低和尿尿酸升高效果优于对照组。结论:四妙汤加味合别嘌呤醇对高尿酸血症病有良好的促进尿酸排泄、降低血尿酸的作用。

Objective：To explore the effect of the damp-heat type hyperuricemia in plasma uric acid by the treatment of＂ Simiaosan Jiawei Decoetion＂.Methods： 80 patients were distributed to two groups,40 in the experimental group were treated by ＂Simiao Jiawei Decoction＂ and allopurinol,40 in the control group were treated by allopurinol for two weeks. The plasma uric acid and urine uric acid were observed before and after treatment .Results：The plasma uric acid reduced and urine uric acid increased obviously in both groups after treatment （P 〈0.05） .The experimental group got better effect than that of the control group. Conclusion：It is indicated that this Decoction and allopurinol is quite effective to promote the discharge of uric acid and reduce plasma uric acid.