过敏性紫癜尿微量蛋白的临床研究

A Clinical Study on the Urine-microprotine of the Anaphylactoid Purpura

目的:探讨过敏性紫癜尿微量蛋白的相关因素。方法:30例过敏性紫癜患者分别在病后1周、4周、3个月和6个月检测尿微量蛋白。结果:ALB、β2-MG、α1-MG在1周、4周、3个月和6个月,IgG在4周、3个月与正常人比较,差异有极显著性意义(P<0.01);不同性别、病程、发病形式比较无显著性差异;伴有腹痛症状IgG与无腹痛患者比较,差异有显著性意义(P<0.05)。结论:过敏性紫癜发病后的一周至半年都存在肾脏损害,伴有腹痛者更明显,且不受性别、病程、发病形式的影响。

Objective：To Explore relative elements of urine-microprotine in anaphylactoid purpura （AP）.Methods： Urine- microprotines were examined in 30 cases of AP after 1 week,4 weeks,3 months, 6 months.Results：There were obviously significant differences in ALB, β2-MG, α1-MG after 1 week ,4weeks, 3 months, 6 months of onset ,IgG after 4weeke,3months compared with normal （P 〈0.01）. There was no significant between the different sexes, course and invasive form,but there was significant in IgG of AP with bellyache compared with no bellyache （P 〈0.05）.Conclusion：Kidney damadge is existed after onset from 1 week to 6 months ,especially more in AP with bellyache, and not affected by sex,course and invasive form.