梗阻性黄疸患者七氟烷麻醉术后苏醒时间的临床观察

Clinical Observation of Recovery Times From Anesthesia with Sevoflurane in Obstructive Jaundice Patients

目的观察梗阻性黄疸患者七氟烷麻醉术后的苏醒时间。方法60例上腹部手术患者,ASAⅠ～Ⅱ级,按血胆红素分为无黄疸对照组,轻度黄疸组,中度黄疸组,重度黄疸组,每组15例。其中黄疸组患者均为梗阻性黄疸。常规麻醉诱导后吸入1%～2%七氟烷,维持BIS值45,术毕即停吸七氟烷。同时记录从停药后至BIS值达到90的时间和唤醒时间。结果黄疸组BIS值达到90的时间和唤醒时间明显大于非黄疸对照组,但黄疸轻,中,重三组之间无明显差异。结论梗阻性黄疸患者七氟烷麻醉术后苏醒时间明显延长,胆红素水平与延长的苏醒时间无明显相关性。

Objective To observe the recovery times after sevoflurane anesthesia in obstructive jaundice patients. Methods Sixty patients（ ASA Ⅰ-Ⅱ level） undergoing abdominal surgery were divided into four groups according to the total bilirubin level in blood： control group without jaundice, mild jaundice group, moderate jaundice group and severe jaundice group, with 15 cases of each group. All the jaundice refer to obstructive jaundice. After conventional inducting of anesthesia, 1% - 2% sevoflurane was used to maintain the BIS value of 45. At the end of the surgery, sevoflurane, the time reached BIS90 and wake-up time were recorded. Results The recovery times of patients with obstructive jaundice prolonged significantly compared with control group after sevoflurane anesthesia. However, no discrepancies were observed among the groups with different levels of bilirubin. Conclusion Recovery from anesthesia with sevoflurane was delayed in obstructive jaundice patients, but the recovery times was not correlated with the the level of bilirubin.