1,4-氧硫杂萘-4,4-二氧化物含氟衍生物的合成

Synthesis of Fluorine-Containing 1,4-Benzoxathiin-4,4-dioxide Derivatives

以含氟的2-(2-氯-4-硝基苯磺酰基)-1-劳基乙酮为原料,在K_OCO_3/TEBA/DMF体系中,与烷基化试剂发生烷基化-环化反应。合成六种未经文献报道的1,4-氧硫杂萘-4,4-二氧化物的含氟衍生物,利用元素分析、IR、~1H NMR、MS对其结构进行了表征。

Six new fluorine - containing 1,4 - benzoxathiin - 4,4 - dioxide derivatives have been synthesized via alkylation - cyclization reaction in K2CO3/TEBA/DMF system. The structures of all these compounds were identified by elemental analysis, MS, IR and 1H NMR spectra.