宫颈病变电环切术临床分析

The Clinical Analysis of Cervix Disease with Loop Electrosurgical Excision Procedure

目的探讨宫颈病变患者行宫颈电环切除术(Leep)的疗效。方法回顾性分析2004年4月至2008年10月本院350例宫颈病变患者进行Leep手术治疗的临床资料。经宫颈薄层液基细胞学(LCT)、人乳头瘤病毒(高危型HPV-DNA)检查阳性、阴道镜活检病理诊断为CIN共310例,其中CINⅠ140例,CINⅡ150例,CINⅢ20例,宫颈糜烂40例患者行Leep术(宫颈锥切),组织送病检。结果Leep术后随访宫颈糜烂100%治愈,CINⅠ、CINⅡ95%治愈;CINⅢ90%治愈。Leep手术时间短、出血少、治愈率高、并发症少、能保留生育功能。结论Leep手术是目前临床治疗宫颈病变的有效方法之一。

Objective To curative effect of cervical intraepithelial neoplasia（CIN） with LEEPconization. Methods All 350 cases with LCT-positive and HPV-positive in our centre from April 2004 to october 2008 were biopsy by colposcopy, and were diagnosed as cervical intraepithelial neoplasia.The eases were dividedintto 4 proups accroding to lesion grade,which was CINⅠ（140） ,CINⅡ（150）, CINⅢ（20） and cervical erosion （40）, and 350 patients were operated by LEEP. Results The curative rate of cervical erosion, CINⅠ, CIN Ⅱ, and CINⅢwere 100%, 95%, 95% and 90%,respectively on 3 month after LEEP operation.LEEP operationtime is shot, the bleeding is few, the curative ratio is tall, complication is few, and be able toreserve procreation function. Conclusion LEEP operation is one of the most effective method for treatment of cervical lesion.