摘要
A molecular template synthetic polymer highly selective for m-nisoldipine was prepared by a molecular imprinting technique.The selective binding characteristics of the template polymer were evaluated by Scatchard analysis and ultraviolet spectrometry.The results showed that the its dissociation constant was estimated to beKd=1.523×10-3mmol/L.The selectivity binding experiment for substrates indicated the polymer gave a high affinity and selectivity for m-nisoldipine.
A molecular template synthetic polymer highly selective for m-nisoldipine was prepared by a molecular imprinting technique. The selective binding characteristics of the template polymer were evaluated by Scatchard analysis and ultraviolet spectrometry. The results showed that the its dissociation constant was estimated to beKa = 1. 523 × 10^-3 mmol/Lo The selectivity binding experiment for substrates indicated the polymer gave a high affinity and selectivity for m-nisoldipine.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2009年第6期903-905,共3页
Chemical Research and Application
基金
河北省科技厅重点资助项目(07276101D-37)
关键词
分子印迹聚合物
间尼索地平
底物选择性
分子识别
molecularly imprinted polymer
m-nisoldipine
substrate selectivity
molecular recognition
