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NCca—ATP通道在急性脊髓损伤继发性损害机制中的影响

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摘要 脊髓损伤后其病理发生发展过程由两种损伤机制主导，即原发性和继发性损伤机制。对于脊髓损伤来说，原发性损伤是一个不可逆转的过程，而继发性损伤则是一个可逆的且可控制的过程。脊髓继发性损伤的机制目前有3种学说：①炎症水肿学说；②自由基和血管机制学说；③细胞凋亡学说旧。新近研究，脊髓损伤与NCca-ATP（activated by intracellular Ca^2＋ and inhibited by intracellular ATP）通道具有密切的联系。对此综述如下。
作者 李熙 许卫红
机构地区 福建医科大学附属第一医院骨科
出处 《中国综合临床》 2009年第6期667-669,共3页 Clinical Medicine of China
关键词 脊髓损伤 NCca—ATP通道 继发性损害 磺脲类受体-1
分类号 R651.2 [医药卫生—外科学] R971.1 [医药卫生—药品]
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中国综合临床
2009年 第6期

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