摘要
目的研究不同低剂量X射线照射孕期SD大鼠后对其仔鼠生长发育的不同影响。方法建立受不同低剂量率组X射线照射的孕SD大鼠模型,对出生的仔鼠进行一般神经体格发育的检测。结果结果表明0.015mGy/ d及0.03mGy/d两个低剂量率,对仔鼠的神经体格发育具有不同程度的生长促进作用;0.06mGy/d的受照射剂量率对仔鼠的生长发育没有明显的影响,而接受0.09mGy/d的受照射剂量率对仔鼠的生长发育呈现出一定的阻碍作用。结论出生前宫内受到低剂量X射线照射对仔鼠的生长发育具有一定的促进作用,随着受照射X射线剂量的增加,这种兴奋作用减弱并对仔鼠的生长发育呈现出一定的阻碍作用。
Objective To study the different influences on the growth of the offsprings of SD rats receiving different low doses of irradiation in the whole pregnant period. Methods To establish SD pregnant rat models receiving different doses of X - ray and observe the impact of irradiation on the growth of the offsprings. Results Low dose rate of 0.015mGy/d and 0.03mGy/d could promote the development of offsprings in a certain extent, the group with dose rate of 0.06mGy/d had little difference. While the group with dose rate of 0.09mGy/d presented holdback in growth. Conclusion Prenatal exposure to low dose radiation X -ray might promote growth of the offsprings. With the dose increasing , this exciting response gradually weakened, and at last presented obstacle response.
出处
《中国辐射卫生》
2009年第2期156-158,共3页
Chinese Journal of Radiological Health
