宫颈液基细胞学检测结果的临床分析

Analysis of Cervical Cytology Detected by TCT Liquid-based Test

目的通过对宫颈液基薄层细胞学(TCT)检查结果的分析,探讨TCT技术在临床诊断上的应用价值。方法1012例门诊患者行TCT检查和TBS细胞学分类诊断,对TCT检查发现异常的患者常规行阴道镜病理检查。结果行TCT检查的1012例中,细胞学阳性病例42例,占4.15%,其中,不典型鳞状细胞(ASCUS)29例,占2.87%,低度鳞状上皮内病变(SIL-L)6例,占0.59%,高度鳞状上皮内病变(SIL-H)5例,占0.49%,鳞状细胞癌(SCC)1例,占0.1%,腺癌(AC)1例,占0.1%。结论TCT技术应用与宫颈细胞涂片筛查,能明显提高涂片满意率及宫颈细胞检出率,减少漏诊率。细胞学阳性病例,联合阴道镜活组织病理检查,能及早发现宫颈早期病变。

Objective To analyze and evaluate the TCT liquid-based test in clinical diagnostic application. Methods 1012 patients in this hospital were examined using TCT and TBS. The abnormal cases selected by TCT were detected by colposcopical pathological examination. Results Among all the 1012 cases examined with TCT technique, 42 cases were positive of the cytological diagnosis（4.15%） to be further analyzed with cell pathology, vaginoscopy and pathologic biopsy, and to be divided into the following subsets.29 cases for atypical squalors cells （ASCUS, 2.87 %）, 6 cases for low grade squalors intraepithelial lesion（SIL-L,0. 59%）, 5 cases for high grade squalors intraepithelial lesion （SIL-H,0.49%）, 1 case for squalors cell carcinoma（SCC, 0. 1 %）, 1 case for adenocarcinoma endometrium （AC, 0. 1%）. Conclusion TCT can increase the satisfactory rate of smears as well detection rate of abnormal cervical cells and decrease the rate of missed diagnosis. Cytological diagnosis combined with vaginoscopy can detect cervical early disease as soon as possible.