香菇多糖联合顺铂胸腔内注入治疗恶性胸腔积液的疗效观察

Effect Observation of Malignant Pleural Effusion Treated with Lentinan and Cisplatin

目的:观察香菇多糖联合顺铂胸腔内注入治疗恶性胸腔积液的疗效。方法:90例恶性胸腔积液患者按随机数字表法分为观察组和对照组,每组45例;均应用中心静脉导管胸腔穿刺置管引流,将顺铂稀释后注入胸腔内治疗,每周1次,共4周;观察组在对照组基础上加用香菇多糖稀释后注入胸腔内治疗,每周2次,共4周。结果:观察组总有效率为88.9%,对照组总有效率为66.7%,观察组疗效优于对照组(P<0.05)。结论:香菇多糖胸腔内注入能够提高恶性胸腔积液治疗的有效率。

Objective：To observe the efficacy of lentinan and cisplatin for malignant pleural effusion. Methods：90 patients with malignant pleural effusion were randomly divided into observation group and control group, with 45 cases in each group. All patients were treated with cisplatin into pleural, but lentinan was given additionally to observation group. Results：The treatment effectiveness of the observation group was 88.9% , and the treatment effectiveness of the control group was 66. 7% （P 〈 0.05 ）. Conclusion：Lentinan could raise the treatment effectiveness for malignant pleural effusion.