加味枳术汤治疗功能性便秘的临床研究

Modified Zhizhu Decoction in the Treatment of Functional Constipation

目的:观察加味枳术汤治疗功能性便秘的治疗效果及停药2周后复发情况。方法:根据罗马Ⅱ便秘诊断标准,排除肠道器质性病变,选取功能性便秘患者76例,随机分为加味枳术汤治疗组40例和服用果导片对照组36例。结果:服药2周后对照组和治疗组总有效率分别为63.9%、90.0%,两组总有效率比较,差异有统计学意义(χ2=7.439 2,P<0.05);停药2周后,对照组和治疗组分别复发11,2例,两组复发率比较,差异有统计学意义(2χ=14.596 8,P<0.05)。结论:加味枳术汤治疗便秘具有明显疗效和较低的复发率。

Objective：To observe the curative effects and long-term effects of Modified Zhizhu Decoction in the treatment of functional constipation. Methods： Base on Roma Ⅱ criteria for elimination of anorectal organic diseases, 76 patients suffered from functional constipation were randomized into treatment group （40 cases） treated with Modified Zhizhu Decoction and control group （36 cases） treated with phenlphthclein tablets . Results： Two weeks after treatment, effective rate in control group and treatment group was 63. 9% and 90.0%, respectively, the difference being significant （χ^2= 7. 439 2, P〈0.05）. Two weeks after drug withdrawal, 11 patients recurred in control group and only 2 patients recurred in treatment group, the difference being statistically significant （χ^2= 14. 596 8, P〈0.05）. Conclusion： Modified Zhizhu Decoction possesses obvious therapeutic effects and lower recurrence rate in treating functional constipation.