小儿急性上呼吸道感染抗菌药物合理使用MTP干预研究

MTP Intervention of Antibiotics Usage in Pediatric Acute Upper Respiratory Infection

目的探讨监测-培训-计划(MTP)合理用药干预模式对小儿急性上呼吸道感染抗菌药物合理使用的干预效果。方法按照WHO/合理用药国际网络(INRUD)选择性用药指标调研方法(SDUIS)设定调研指标,选取2006年6-8月儿科门诊急性上呼吸道感染处方作为调研基线,采用MTP模式进行干预,1个月后统计分析干预后的调研指标,然后再干预再调研,如此不断循环。结果经过4轮MTP循环后,小儿急性上呼吸道感染使用抗菌药物百分率、使用注射剂百分率、使用抗菌药物注射剂百分率,每次就诊平均药费由干预前的75.00%、61.67%、40.33%、54.29元分别下降到干预后的7.00%、5.00%、3.00%、39.16元(均P<0.05)。结论MTP合理用药干预模式有效提高小儿急性上呼吸道感染抗菌药物合理使用水平。

OBJECTIVE To study the effect of the intervention of monitoring-training-planning（MTP） on use of antibacterials and injections for pediatric acute upper respiratory infection. METHODS In accordance with selected drug use indicators（SDUIS）, the pediatric outpatient prescription of acute upper respiratory infection was selected in our hospital from Jun to Aug 2006 as the baseline,and intervented by MTP, then the investigation of postinterfervention was carried out after a month, and then re-intervention research was made, so the cycle continued. RESULTS The percentage ratio of antibacterials, and injection usage, and the average drug fee in pediatric outpatient prescription for acute upper respiratory infection in our hospital was decreased from 75.00%, 61.67%, 40. 33% and 54.29 yuan to 7.00%, 5.00%, 3.00% and 39.16 yuan, respectively after four rounds of MTP （all P〈0.05）. CONCLUSIONS The intervention mode of MTP is feasible and effective on promoting the rational use of antibacterials for pediatric acute upper respiratory infection in our hospital.