慢性肾功能衰竭血液透析住院患者并发感染的临床分析

CLINICAL ANALYSIS OF CONCURRENT INFECTION IN HOSPITALIZED PATIENTS WITH CHRONIC RENAL FAILURE UNDERGOING HEMODIALYSIS

目的了解慢性肾功能衰竭维持血液透析住院患者合并感染的发生情况,探讨其感染的特点。方法回顾性调查近2年我院慢性肾功能衰竭维持血液透析患者住院病史,收集并统计血液透析合并感染患者的临床资料。结果调查血液透析患者159例,住院发生感染67例,各部位发生感染173例次。其中肺部感染居首位,占48.6%,以革兰阴性菌为主;其次是肠道感染及导管感染。分别占16.8%和14.5%。肺部感染临床情况复杂,肠道感染与使用抗生素后继发二重感染有关,导管感染与留置时间相关。复合菌感染和多部位感染均超过10%,且病情严重,预后往往不佳。结论血液透析住院患者合并感染发生率高,感染种类及病原菌组成复杂,以肺部感染最常见。

Objective To investigate the morbidity and characteristic of concurrent infection in chronic renal failure hospitalized patients undergoing hemodialysis. Methods Medical records of hemodialysis patients in our hospital last two years were enrolled, the clinical data of hemodialysis patients developed concurrent infection were analyzed respectively. Results Among 159 hemodialysis patients ,67 developed concurrent infection in hospital, 173 concurrent infections developed in variant part of patients＇ body. Pulmonary infection was the most common infection（48. 6% ） ,the main pathogens were Gram negative bacterium. Intestines infection and catheter infection were the secondary. the rate was 16.8% and 14.5% respectively. Pulmonary infection was really complicated. The second intestines infection because of antibiotic use. Catheter infection was related to the time of indwelling. The complicated mixed micro - organisms infection and mixed sites infection were all over 10%. The prognosis is bad. Conclusion The prevalence of concurrent infection was high in hospitalized patients undergoing hemodialysis. The characteristic of the infection was complicated,Pulmonary infection was the main infection.