摘要
胆酸是哺乳动物体内合成的一种天然化合物,具有特殊的分子结构和优良的生物适应性。由胆酸合成的高分子化合物保持了胆酸的部分性质,如双亲性、手性、侧基反应活性和自组装性能等。在化学和药学领域,含胆酸高分子材料具有重要的应用价值。本文从自由基聚合形成的含胆酸高分子化合物、胆酸修饰的高分子化合物和胆酸缩聚物等几个方面综述了含胆酸高分子化合物的制备和特性,并对胆酸在高分子材料方面的新用途作了展望。
Cholic acid is a natural compound that is synthesized in the animal body, which has special chemical structure and good biocompatibility. Polymers prepared from cholic acid can preserve some properties of cholic acid, such as facial amphiphilicity, chirality, reactivity of the side groups and capacity of self-assembiling. In chemical and pharmaceutical fields, polymeric materials containing cholic acid can be used widely. This paper reviews the preparation and characterization of polymers containing cholic acid obtained by free radical polymerization, polymers modified with cholic acid and polycondensation of cholic acid, etc. The development of polymers containing cholic acid in the future is also forecasted.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2009年第6期1304-1311,共8页
Progress in Chemistry
基金
天津市科技计划项目(No.08ZXCXSH05300)资助
关键词
胆酸
高分子材料
制备
特性
cholic acid
polymer material
preparation
characterization
