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地特胰岛素在糖尿病基础-餐时治疗模式中的应用 被引量:1

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摘要 糖尿病(DM)是以高血糖为主要特征的慢性进行性疾病。相对或绝对的胰岛素分泌不足是DM的主要病因,因此胰岛素的补充治疗是十分重要的治疗措施之一。从治疗的角度看,为实现血糖控制达标、最大程度地保护残存胰岛B细胞数量、恢复胰岛B细胞功能、缓解DM病情、降低DM并发症及相关心血管风险等目标,较理想的策略是最大程度地利用药物或/和胰岛素模拟生理性胰岛素分泌,即采用基础+餐时治疗模式。
出处 《药品评价》 CAS 2009年第6期252-255,共4页 Drug Evaluation
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  • 1Hollander P,Cooper J,Bregnhφj J,et al.A 52-week,multinational,openlabel,parallel-group,noninferiority,treat-to-target trial comparing insulin detemir with insulin glargine in a basal-bolus regimen with mealtime insulin aspart in patients with type 2 diabetes[].Clinical Therapeutics.2008
  • 2Raskin P.Efficacy and safety of insulin detemir[].Journal of Endocrinology and Metabolism.2007
  • 3Yenigun M,Honka M.Switching patients from insulin glargine-based basal-bolus regimens to a once daily insulin detemir-based basal-bolus regimen:results from a subgroup of the PREDICTIVE study[].International Journal of Clinical Practice.2009
  • 4Heise T,Pieber TR.Towards peakless,reproducible and long-acting insulins.An assessment of the basal analogues based on isoglycaemic clamp studies[].Diabetes Obesity and Metabolism.2007
  • 5Duckworth W,Abraira C,Moritz T,et al.Glucose control andvascular complications in veterans with type 2 diabetes[].The New England Journal of Medicine.2009
  • 6L.F. Meneghini,K.H. Rosenberg,C. Koenen.Insulin detemir improves glycaemic control with less hypoglycaemia and no weight gain in patients with type 2 diabetes who were insulin naive or treated with NPH or insulin glargine: clinical practice experience from a German subgroup of the PREDICTIVE st[].Diabetes Obesity and Metabolism.2007
  • 7S. Sreenan,A. Virkamaki,K. Zhang,J.B. Hansen.The PREDICTIVE study group. Switching from NPH insulin to once-daily insulin detemir in basal-bolus treated patients with diabetes mellitus: data from the European cohort of the PREDICTIVE study[].International Journal of Clinical Practice.2008
  • 8L.F. Meneghini,C. Koenen,W. Wend,J. Selam.The usage of a simplified self-titration dosing guideline (303 Algorithm) for insulin detemir in patients with type 2 diabetes - results from the randomized, controlled predictive 303 Study[].Diabetes Obesity and Metabolism.2007

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