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2种药物雾化吸入治疗毛细支气管炎的最小成本分析 被引量:1

Dexamethasone vs.Budesonide for Bronchiolitis:Cost-minimization Analysis
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摘要 目的:评价地塞米松与布地奈德短期雾化吸入治疗毛细支气管炎的疗效与经济效果。方法:采用回顾性分析方法,对氧气驱动雾化吸入地塞米松(国产)和布地奈德(进口)治疗毛细支气管炎的疗效进行对比,并进行最小成本分析。结果:地塞米松组与布地奈德组的总有效率分别为93%、92%(P>0.05);平均医疗总费用和激素药费分别为(1258.73±131.04)元、(8.94±1.45)元和(1385.39±175.61)元、(167.28±24.86)元,差异均有统计学意义(P<0.01)。结论:短期雾化吸入地塞米松治疗小儿毛细支气管炎不但安全、有效,而且更加经济,适合于低收入家庭的患儿使用。 OBJECTIVE: To evaluate the curative efficacy and economic efficacy of dexamethasone vs. budesonide short - term inhalation for bronehiolitis. METHODS: By retrospective analysis, the curative efficacy of oxygen- driven inhalation of dexamethason (made in China) vs. budesonide (imported preparation) in the treatment of bronchiolitis were evaluated and a cost- minimization analysis was performed. RESULTS: In dexamethasone- treated group vs. budesonide- treated group, the total effective rate was 93% vs. 92% (P〉0.05). The average total medical expense and the cost of hormone drugs in dexam- ethasone - treated group vs. budesonide - treated group were(1 258.73±131.04) yuan and(8.94±1.45) yuan, respectively vs. (1 385.39±175.61) and (167.28±24.86) yuan, respectively, showing significant differences between the two groups(P〈 0.01). CONCLUSION: Short- term inhalation of dexamethasone is suitable for bronchiolitis children from low income family in that it is safe and effective but more economical than budesonide.
作者 孙琦 张亚明
出处 《中国药房》 CAS CSCD 北大核心 2009年第17期1283-1285,共3页 China Pharmacy
关键词 毛细支气管炎 糖皮质激素 雾化吸入 疗效 最小成本分析 Bronchiolitis Glucocorticoid Inhalation Therapeutic efficacy Cost-minimization analysis
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