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我院实施监管措施对喹诺酮类药临床应用的影响

Application of Quinolones Evaluated from Perspective of Its Consumption Sum before and after the Enforcement of Regulatory Measures
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摘要 目的:了解实施监管措施对喹诺酮类药临床应用的影响。方法:分析我院实施监管措施前、后应用喹诺酮类药的主要科室中,喹诺酮类药销售金额、销售金额占总销售金额百分比的变化情况。结合同期归档病历检查结果,评价用药是否合理。结果与结论:呼吸内科等6个科室为我院应用喹诺酮类药的主要科室;实施监管措施后,我院多数科室喹诺酮类药销售金额均减少,表明监管措施取得了一定成效。 OBJECTIVE: To evaluation the effects of the regulatory measures on the clinical application of quinolones. METHODS: The consumption sum and its proportion in the total in major clinical departments before and after the enforce- ment of the regulatory measures were analyzed, which were compared with the data from the synchronous case files so as to evaluate the rationality of the use of quinolones. RESULTS & CONCLUSION: Quinolones were predominantly used in six departments including the department of respiratory diseases. After the initiation of the regulatory measures, the consumption sum of quinolones decreased in most departments, suggesting the positive effect of the regulatory measures.
出处 《中国药房》 CAS CSCD 北大核心 2009年第17期1300-1302,共3页 China Pharmacy
关键词 喹诺酮类药 销售金额 监管措施 Quinolones Consumption sum Regulatory measures
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  • 1Aarestrup FM, Seyfarth AM, Emborg HD, et al .Effect of abolishment of the use of antimicrobial agents for growth promotion on occurrence of antimierobial resistance in fecal enteroeocci from food animals in denmark[J]. Antimicrob Agents Chemother, 2001,45(7): 2 0154.
  • 2Hawkey PM.Mechanisms of quinolone action and microbial response[J] .J Antimicrob Chemother, 2003, 51(Suppl 1):29.
  • 3Austin DJ, Kristinsson KG,Anderson RM. The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance[J].Proc Natl Acad Sci USA, 1999,96(3): 1 152.
  • 4Martens R, Wetzstein HG, Zadrazil F, et al. Degradation of the fluoroquinolone enrofloxaein by wood - rotting fungi[J] .Appl Environ Microbiol, 1996, 62(11):4 206.
  • 5Friedman SM, Lu T, Drlica K. Mutation in the DNA gyrase A gene of escheriehia coil that expands the quinolone resistance-determining region[J].Antimicrob Agents Chemother, 2001,45(8): 2 378.
  • 6Hooper DC.Emerging mechanisms of fluoroquinolone resistance [J]. Emerg Infect Dis, 2001,7(2): 337.
  • 7Yang H, Chen S,White DG, et al .Characterization of multiple- antimierobial - resistant Escherichla coli isolates from diseased chickens and swine in China[J] .J Clin Microbiol, 2004,42 (8) :3 483.
  • 8Ling JM, Chan EW, Lam AW, et al. Mutations in topoisomerase genes of fluoroquinolone resistant salmonellae in Hongkong[J].Antimicrob Agents Chemother ,2003,47(11): 3 567.
  • 9Luo N, Pereira S, Sahin O, et al .Enhanced in vivo fitness of fluoroquinolone - resistant Campylobacter jejuni in the absence of antibiotic selection pressure[J] .Proc Natl Acad Sci USA ,2005,102(3):541.
  • 10Cloeckaert A, Chaslus- Dancla E. Mechanisms of quinolone resistance in Salmonella [J]. Vet Rex, 2001,32(3-4):291.

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