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非神经性乙酰胆碱系统的结构和功能特征 被引量：6

The structure and function of non-neuronal acetylcholine system
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摘要 非神经性乙酰胆碱系统包括乙酰胆碱、胆碱乙酰转移酶、胆碱酯酶、毒蕈碱乙酰胆碱能受体和烟碱胆碱能受体,广泛地存在于角质化细胞、肿瘤细胞、内皮细胞、胶质细胞、上皮细胞、淋巴细胞、生殖器官等非神经性细胞和组织,参与这些细胞和组织的功能调节,并与一些疾病的病理生理变化相关。本文归纳了非神经性乙酰胆碱系统的概况,并具体介绍了内皮细胞、胶质细胞、上皮细胞和淋巴细胞的非神经性乙酰胆碱系统的结构和功能特征。非神经性乙酰胆碱系统不但与神经性乙酰胆碱系统不尽相同,而且不同组织的非神经性乙酰胆碱系统也不完全一样。 The Non-neuronal Acetylcholine System, including acetylcholine （ NNAs）, choline acetyhransferase, acetylcholinesterase, muscarinic and nicotinic ACh receptors, has been identified in numerous non-neuronal ceils and tissues, including keratinocytes, cancer cells, immune cells and reproductive organs. NNAs is involved in regulation of their function and related to the pathophysiology of several diseases. This review investigates the research progress of NNAs and describes the structure and function of NNAs in different cells, such as glial cell, endothelium,epithelia and lymphocyte. NNAs is not the same as neuronal acetylcholine system, neither is the same in different cells.
作者 葛徐林 汪海
机构地区 军事医学科学院卫生学环境医学研究所 军事医学科学院毒物药物研究所
出处 《中国药理学通报》 CAS CSCD 北大核心 2009年第6期712-715,共4页 Chinese Pharmacological Bulletin
关键词 非神经性乙酰胆碱 胶质细胞 内皮细胞 上皮细胞 淋巴细胞 non-neuronal acetylcholine glial cell endothelium epithelia lymphocyte
分类号 R-05 [医药卫生] R329.2 [医药卫生—人体解剖和组织胚胎学]
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参考文献29

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共引文献17

同被引文献39

引证文献6

二级引证文献28

中国药理学通报
2009年 第6期

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