细胞间黏附分子-1及血管细胞黏附分子-1与突发性耳聋

Intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 in sudden hearing loss

突发性耳聋的发病机制目前尚未阐明。近年来,国外学者报道突发性耳聋患者血浆中细胞间黏附分子-1(ICAM-1)和血管细胞黏附分子-1(VCAM-1)水平增高。现将有关突发性耳聋与ICAM-1和VCAM-1关系作一综述,为突发性耳聋的发病机制及治疗提供新的思路。

The etiopathogenesis of sudden hearing loss（SHL） is not clear yet. In recent years, several authors reported that serum levels of inter cellular adhesion molecule-1 （ ICAM-1 ） and vascular cell adhesion molecule-1 （VCAM-I） were higher in patients affected by SHL. In this article the relationship between SHL, ICAM-1 and VCAM-1 was reviewed to provide new ideas for evaluation the pathogenesis and the treatment of SHL.