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宫颈癌28例新辅助化疗临床疗效分析

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摘要 目的探讨新辅助化疗辅助治疗Ⅱa期至Ⅱb期宫颈癌的临床效果。方法宫颈癌患者28例术前采用2个疗程的静脉化疗,化疗结束后10~14d全部行宫颈癌根治术。通过观察患者病灶大小的改变、化疗毒副反应、术中术后并发症等,评价新辅助化疗在宫颈癌治疗中的作用。结果新化疗有效22例,其中4例完全缓解。Ⅱa期有效16例,Ⅱb期有效6例,两者比较差异无显著性(P〉0.05)。化疗效果与期别无关,而与病理类型有关,鳞癌的有效率明显高于腺癌(P〈0.05)。化疗毒副反应轻微。所有患者化疗后均进行宫颈癌根治术。结论宫颈癌术前新辅助化疗可以缩减肿瘤的体积和范围、降低肿瘤的分期,是有效治疗方法。
出处 《湘南学院学报(医学版)》 2009年第2期35-37,共3页 Journal of Xiangnan University(Medical Sciences)
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