玻璃酸钠联合利多卡因关节腔注射对膝关节骨关节炎疼痛影响观察

Effect of the knee injection of sodium hyaluronate plus Lidocaine to the patients who suffer with pain because of the knee osteoarthritis

目的观察玻璃酸钠联合利多卡因行关节腔注射对膝关节骨关节炎疼痛的临床治疗效果。方法将90例膝关节骨关节炎患者随机分为试验组(EG)、对照组(CG)两组,每组为45例,两组在年龄及性别等方面无明显差异。试验组行玻璃酸钠和利多卡因联合注射,对照组行玻璃酸钠和生理盐水联合注射,每周1次,连续5周为1个疗程。对比观察两组治疗后8min时疼痛变化。结果试验组在注射后8min时疼痛缓解情况与对照组比较差异具有统计学意义(P<0.05)。结论玻璃酸钠联合利多卡因行关节腔内注射可迅速缓解运动疼痛。

Objective To study how the pain relieves after combined intra-articular injection of sodium hyaluronate and Lidocaine on knee in patients with osteoarthritis （OA）. Methods 90 cases associated with OA were divided into two groups, experimental group（EG） and control grouP（CG） ,45 cases per group. The ages and genders are no different with each other. EG received a treatment of taking hyaluronate plus Lidocaine. CG received a treatment of taking hyaluronate plus Balanced Saline. Each case receives I injection once a week. And 5 injections are as a course of treatment. Observe how the pain relieves between EG and CG 8 minutes later each time. Results The different in relieving pain. between EG and CG has statistic value （ P 〈 0. 05）. Concluslon Combined intra-articular injection of sodium hyaluronate and Lidocaine on knee can relieve the pain promptly, and the effect is better than that injection with hyaluronate plus Balanced Saline.