以癌胚抗原升高为首发表现的甲状腺髓样癌6例报告

Medullary thyroid carcinoma with the first complaint of serum CEA elevated:a report of 6 cases

目的探讨以癌胚抗原(CEA)升高为首发表现的甲状腺髓样癌的诊治方法。方法回顾性分析北京医院普外科2002年1月至2008年6月收治6例以CEA升高为首发表现的甲状腺髓样癌的临床资料。结果6例病人在常规体检时发现CEA升高,经过全面体检排除了CEA升高的常见疾病,发现有甲状腺结节,行甲状腺肿瘤手术治疗,病理证实为甲状腺髓样癌,术后随访至今均存活,肿瘤无复发。结论CEA升高是甲状腺髓样癌较为常见的临床表现之一,临床鉴别CEA升高疾病时应考虑到甲状腺髓样癌的可能。

Objective To study the experiences in diagnosis and treatment of medullary thyroid carcinoma （MTC） with the first complaint of serum CEA elevated. Methods The clinical data of 6 MTC patients with the first complaint of serum CEA elevated treated from January 2002 to June 2008 at Beijing Hospital was reviewed retrospectively. Results Six patients were found serum CEA elevated in regular physical examination. After precluding the most common diseases, it found all of them had thyroid nodules. Then they underwent thyroidectomy with or without modified neck dissection, and they have been all alive by now without carcinoma recurrence. Conclusion Serum CEA elevated is one of the relatively frequent symptoms in MCT patients. Surgeons should consider it in the differential diagnosis.