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预防性药物干预对糖尿病并急性心肌梗死急诊冠状动脉介入治疗中无复流的影响 被引量:2

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摘要 目的:明确急性心肌梗死(AMI)并糖尿病冠状动脉介入治疗(PCI)前药物干预是否可以有效预防PCI过程中无复流现象。方法:首先将入选患者按照PCI是否出现无复流分为无复流组和正常血流组,然后对药物干预情况、生化、PCI情况等进行Logistic分析,明确药物干预与无复流的关系。结果:他汀类药物是AMI并糖尿病行PCI出现无复流的保护因子[χ2=9.360,P=0.002,Exp(B)=0.309),服用时间≥3个月的无复流发生率明显降低(3.8%,10.9%,χ2=5.413,P=0.020)。而血管紧张素转化酶抑制剂类、β受体阻滞剂、阿司匹林对无复流的发生无明显影响(P>0.05)。结论:长期服用他汀类药物可以减少AMI并糖尿病PCI中无复流的发生。
出处 《临床心血管病杂志》 CAS CSCD 北大核心 2009年第6期410-412,共3页 Journal of Clinical Cardiology
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