Belenil缓释剂与Butalex缓释剂对瑟氏泰勒虫病的防治效果比较

Comparison of treatment effect between Belenil retarder and Butalex retarder for theileriosis

本实验将试验牛进行瑟氏泰勒虫人工感染,然后分别用Belenil缓释剂和Butalex缓释剂制备的长效土霉素对感染牛深部肌肉注射进行治疗。药物组的试验牛经人工感染后,染虫率逐渐增高,最高达到1.5%,红细胞压积(PCV)逐渐下降,红细胞数(RBC)明显下降。注射缓释剂药物治疗42d后,Belenil组染虫率降到0.05%;Butalex组染虫率降至0,血液指标也明显改善,PCV逐渐回升,但在投药42d以后,PCV又呈逐渐下降趋势。Butalex组治疗后,可使RBC回升至7.55×1012/L,Belenil组治疗最高可使RBC回升至6.37×1012/L。试验结果表明,Butalex制剂对瑟氏泰勒虫感染牛的治疗效果好于Belenil制剂。

In this study, cattle were infected artificially with T.sergenti and then Belenil retarder and the Butalex retarder combined with Dexycline were taken respectively to inject into the deep part muscles to cure the infected cattle. After artificial infection, infection rates of red blood cells in treated groups were increasing gradually, the highest value was 1.5 %, and the PCV was falling off, the RBC was decreasing obviously. After 42 days of injecting retarder treatment, the lowest infection rates of red blood cells in group Belenil was 1.5 %, and group Butalex was zero, the blood index was improving obviously, and the PCV was rising gradually, but, after 42 days of treatment, the PCV showed downtrend. The highest RBC with Butalex treatment was 7.55×10^122/L, and the highest RBC with Belenil treatment was 6.37×10^12/L. With artificial infection, there was no typical continued fever, the highest body temperature was 40.5℃ o The results showed that the Butalex retarder was better than the Belenil retarder on the therapeutic efficacy to the T.sergenti infected cattle.