急性脑梗死患者C反应蛋白水平与病情及预后的关系

The relationship among the serum C reactive protein,clinical features and prognosis in patients with acute cerebral infarct

目的探讨急性脑梗死患者血清C反应蛋白(CRP)与病情及预后的关系。方法测定65例急性脑梗死患者血清CRP含量,并与30名体检健康者进行对照,同时对急性脑梗死患者血清CPR水平与病情进行相关分析。结果脑梗死组血清CRP水平高于对照组(P<0.01);脑梗死不同临床分型间血清CRP水平比较,重型组高于中型、轻型组,差异均有显著性(P<0.05);脑梗死预后好转组CRP水平低于无好转组(P<0.05)。结论急性脑梗死患者血清CRP水平升高提示病情重、预后差;早期测定CRP水平有助于评估急性脑梗死的病情及预后。

Objective To discuss the relationship among the serum C reactive protein（CRP） ,clinical features and prognosis in patients with acute cerebral infarct（ACI）. Methods The serum CRP levels of 65 ACI patients were measured and were compared with the serum CRP levels of 30 healthy persons in the corresponding period. Then the relationship between the serum CRP levels and the severity of disease was analyzed. Results The serum level of CRP in patients was higher than that in normal controls（P〈0. 01）. CRP levels were different significantly among different patients with varied clinical features. CRP levels in the severe cases were higher than those of the intermediate and mild case （P〈0. 05）. CRP levels in patients with benign outcome were lower than that of the patients with severe outcome（ P 〈0. 05）. Conclusions The CRP levels of patients with cerebral infarction can predict patient＇s condition and prognosis. Early determination of CRP is helpful to evaluate them.