摘要
目的:探讨护脉膏及喜疗妥对长春瑞滨致兔耳缘静脉损伤的保护作用。方法:在兔耳缘静脉注射长春瑞滨前10min,将护脉膏及喜疗妥分别涂在兔耳缘静脉及周围,厚度为3mm,4h后重涂1次。分别在24h后、7天后、15天后,采用彩色多普勒超声检测兔耳缘静脉,比较其内膜及管壁的变化;同时取标本,观察兔耳缘静脉病理学改变,并与对照组比较。结果:护脉膏及喜疗妥对长春瑞滨致兔耳缘静脉急性病理损伤、亚急性病理性损伤、慢性病理性损伤均有良好的保护作用,但护脉膏的保护作用明显优于喜疗妥。结论:两种防护措施对长春瑞滨致兔耳缘静脉损伤均有良好的保护作用。
Objective:To investigate the effects of Humai cream and Hirudoid on preventing rabbit ear veins injury caused by Navelbine.Metbods:The rabbit ear veins and surrounding skin was treated with Humai cream and Hirudoid 3 mm in thickness, 10 minutes before and 4 hours after the injection of Navelbine. The color Doppler used to detect the changes of tunica intima and vessel wall in 24 hours, 7 days and 15 days, the veins were also observed histopathologically under light microscope. Results:Both Humai cream and Hirudoid can prevent pathological injury on rabbit ear veins caused by Navelbine, but the effect of Humai cream is significantly better. Conclusion: Both Humai cream and Hirudoid has good effects on preventing vein injury caused by Navelbine.
出处
《医学影像学杂志》
2009年第5期619-621,共3页
Journal of Medical Imaging