血小板计数增高与食管癌临床病理因素的相关性分析

Correlation between thrombocytosis and clinicopathologic factors in esophageal carcinoma

目的:探讨血小板增多与食管癌临床病理因素的关系。方法:比较150例食管癌患者及360名正常人血小板水平。血小板计数≥300×109L-1定义为血小板增多。结果:正常人群及食管癌患者血小板水平分别为(204±114)×109L-1和(289±125)×109L-1,血小板增多患者比例与浸润深度(P=0.010)、淋巴结转移(P=0.003)有关。结论:血小板与食管癌发展、转移有关,血小板增多能预测食管癌患者分期及预后。

OBJECTIVE：To explore the clinicopathologic significance of thrombocytosis in the patients with esophageal carcinoma. METHODS：Platelet counts were detected in 150 cases of esophageal carcinoma and 360 healthy people as control. Thrombocytosis was defined as a platelet count of at least 300 × 10^9 L^-1. RESULTS： Platelet counts in the patients with esophageal carcinoma and healthy people were （289±125） × 10^9 L^-1 and （204±114） × 10^9 L^-1, respectively. Platelet counts were significantly increased in patients with deep tumor （P= 0. 010） and nodal involvement （P = 0. 003）. CONCLUSION： Thrombocytosis is associated with tumor progression and metastasis and may be a predictor of prognosis in esophageal cancer.