腹腔镜胆囊切除术后恶心呕吐预防性用药的META分析

Meta analysis on prophylactic medication for prevention of nausea and vomiting after laparoscopic cholecystectomy

目的用循证医学的方法评价腹腔镜胆囊切除术后恶心呕吐的预防性用药的作用。方法采用随机效应模型Meta分析,统计分析最近在国内外期刊上发表的具有可比性的3篇文献。结果恩丹西酮与恩丹西酮联合地塞米松应用预防腹腔镜胆囊切除术后恶心呕吐没有差异。结论Meta分析表明单独应用恩丹西酮即可达到恩丹西酮联合地塞米松预防腹腔镜胆囊切除术后恶心呕吐的功效。

Objective To evaluate the prophylactic medication for the prevention of nausea and vomiting after laparoscopic cholecystectomy by means of evidence-based medicine. Methods Meta analysis with random effect model was used to analyse 3 comparable literatures published recently. Results There is not statistical difference between ondansetron treated group and the combination of ondansetron with dexamethason treated group for the prevention of nausea and vomiting after laparoscopic cholecystectomy. Conclusion Single ondansetron using can reach the function of ondansetron combination with dexamethason treated for the prevention of nausea and vomiting after laparoscopic choleeystectomy.