634株胆汁分离菌鉴定及耐药性分析

Germiculture of 634 strains of bacteria in bile and antibiotic susceptibility test

目的:了解胆汁中病原菌的分布和耐药状况。方法:回顾性分析667份临床胆汁标本中分离的致病菌分布及药敏结果。结果:分离的634株致病菌中,革兰阳性菌248株,革兰阴性菌369株,念珠菌17株。革兰阳性球菌中以肠球菌属为主,共210株(84.7%);革兰阴性杆菌中以大肠埃希菌为主,共162株(43.9%)。革兰阳性菌对万古霉素耐药率最低,革兰阴性菌对阿米卡星耐药率最低。结论:胆汁分离菌的鉴定及耐药性分析结果可以指导临床选择敏感药物。

Objective： To study the distribution and drug susceptibility of pathogenic bacteria in the bile samples. Methods： The distribution and drug resistance of 634 strains of pathogenic bacteria isolated from the bile samples were analyzed retrospectively. Results：Among the 634 strains isolated ,248 were Gram positive bacteria, 369 Gram negative bacteria and 27 fungus. Two hundred and ten strains of the G^＋ bacteria were Enterococcus and 162 strains of G^- bacteria were E. coll. G^- bacteria were the most susceptible to vancomycin, while G^- bacteria were the most sensitive to amikacin. Conclusions ： As the amount of pathogenic bacteria, the distribution of microbial population in the bile and their drug resistance to antibiotics are changing, proper antibiotics should be chosen in accordance to the results of germiculture.