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食管癌的表观遗传学特征

Epigenetic characteristics of esophageal cancer
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摘要 表观遗传学是一门研究基因表达的学科,经典的表观遗传学包括DNA甲基化和组蛋白修饰,microRNA对基因表达的调控也属于表观遗传学的范畴。食管癌发生过程中表观遗传学的改变已成为目前的研究热点,为食管癌的早期诊断、治疗和预后提供了新的手段。 Epigenetic is a subject of gene expression research. Canonical epigenetics includes DNA methylation and histone modification. MicroRNA is also an important part of epigenetics. Study on epigenetic changes becomes a hot spot during esophagus tumorgenesis. Epigenetics may become a novel tool for esophageal cancer early detection, treatment and prediction.
作者 黄锦 杨云生 郭明洲
机构地区 中国人民解放军总医院消化科
出处 《胃肠病学和肝病学杂志》 CAS 2009年第6期493-495,共3页 Chinese Journal of Gastroenterology and Hepatology
关键词 表观遗传学 食管癌 甲基化 组蛋白修饰 MICRORNA Epigenetics Esophageal cancer Methylation Histone modification MicroRNA
分类号 R735.1 [医药卫生—肿瘤]
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参考文献28

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胃肠病学和肝病学杂志
2009年 第6期

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