初发性生殖器疱疹的疗程与远期疗效的相关性研究

Relative research of treatment period and long.dated effects for primary genital herpes

目的探讨初发性生殖器疱疹的疗程与远期疗效的关系。方法用阿昔洛韦和转移因子联合治疗初发性生殖器疱疹，通过长程（3个月）、中程（1个月）、短程（7天）三种不同的疗程治疗，随访1年，观察其治疗后期复发率。结果痊愈率和有效率在长程组最高，分别为50．00％和84．21％，中程组分别为22．86％和54．29％，短程组分别为2．94％和23．53％，三组差异均有统计学意义（P〈0．05）。结论初发性生殖器疱疹患者治疗后的远期疗效长程最佳，其次为中程组，短程组最差。

Objective To explore the relations of treatment period and long-dated effect for primary genital herpes. Methods Primary genital herpes was treated with combination of transfer factor and acyclovir. The pationts were devided into three groups： long period group treated for three months, middle period group for one months and short period group for seven days. The recurrence of post-treatment was observed after 1 year. Results The long period group had the highest cure rate and effective rate, they were 50.00% and 84.21% respectively, the rates of 22.86% and 54.29% in the middle period group, the rates of 2.94% and 23.53% in the short period group, there were differences between each group（ P 〈 0.05）. Conclusions The long period group of genital herpes had the highest cure rate and effective rate, the next was middle period group, the short period group had the lowest rate.