粤东地区四种性传播疾病病原感染的流行状况

Prevalent status of 4 sex transmitted disease agents infection in east Guangdong

目的了解粤东地区人群中4种常见性传播疾病病原感染的流行状况。方法收集2004至2008年就诊于本院门诊的4404例疑似泌尿生殖道感染患者的分泌物样本，采用实时荧光定量PCR法检测淋病奈瑟菌（NG）、沙眼衣原体（CT）、解脲支原体（UU）和单纯疱疹病毒2型（HSV-Ⅱ）感染状况。结果在疑似各病原感染的病例中，UU、NG、CY和HSV-Ⅱ的感染率分别是41．90％（864例）、10．70％（72例）、12．90％（192例）和12．90％（24例）；1152例阳性病例中，感染多集中在20．40岁年龄之间，占86．55％（997／1152）；在感染的性别构成上以女性多见，男女之比为34．38％：65．62％。结论粤东地区人群中4种常见性传播疾病病原的感染率较高，以UU为主，高危人群以20～40岁女性为主，积极对本地区高危人群开展性传播疾病病原体的筛查可有效降低相关疾病的发生。

Objective To investigate the infection situation of Ureaplasma urealyticum, Nersseria gonorrhoeae, Chlamydia trachomatis and HSV-Ⅱ among the people in east Guangdong. Methods 4404 cases of out-patients with serf-clinical symptoms or suspicious reproductive tract infection were selected as study subject and were examined for UU, NG, CT and HSV-Ⅱ. Results Among the 4404 cases, 864 cases were UU positive（41.90% ）, 72 were NG positive （10.70%）, 192 were CT positive（12.90%） and 24 were HSV-Ⅱ positive（12.90%）. Of the 1152 cases of above positive patients, the highest infection rate was in the patients of 20 to 40 years old（86.55 % ）, and the females were obviously higher than the males. Conclusions In the people of east Guangdong, the situation of UU, NG, CT and HSV-Ⅱ infection was severe, especially in 20 to 40 ages. It is very important to detect the sex transmitted disease agents in high risk people and is also the key hnk to control UU, NG, CT and HSV-Ⅱ infection.